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Fighting Inflammation by Inhibiting LOX Enzymes with Boswella

4th March 2007 by Arrow Durfee Posted in Uncategorized

This article from Life Extension gives a great review on the research done of the herb Boswella. They suggest its use for arthritis, colitis, irritable bowel, asthma, pulmonary emphysema, cystic fibrosis, chronic bronchitis and acute respiratory distress syndrome and may proivde protection from cancer. Go to the following link to read the 2 page article in its entirety at the Life Extension site. A worthy read.
Article excerpt:

With the removal of Vioxx® from the market, and sales of other drugs in this class plummeting, scientists are working overtime to identify natural agents that safely block the underlying factors that give rise to inflammation in the body.

Researchers have focused their microscopes on the herb boswellia, which works to block a lethal pro-inflammatory enzyme called 5-lipoxygenase (5-LOX). Until now, only limited strategies have been available to fight the insidious effects of 5-LOX, a potent contributor to inflammatory processes involved in diseases as diverse as cancer, atherosclerosis, arthritis, inflammatory bowel disease, and asthma.

Boswellia Basics
For thousands of years, folk medicine practitioners have used the herb boswellia (Boswellia serrata) to treat a wide range of conditions that we now know are caused by inflammation. This herbal extract is derived from gum resin secreted by the boswellia tree, part of a family of medicinal plants grown and used in India, Africa, China, and the Middle East.

Fighting Inflammation by Inhibiting LOX Enzymes
In the late 1970s, researchers discovered that boswellia produces notable anti-inflammatory effects that are distinct from those produced by nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and aspirin.

NSAIDs quell inflammation primarily by inhibiting the cyclooxygenase-2 (COX-2) enzyme.1 Unfortunately, NSAIDs also block the COX-1 enzyme, which is needed to maintain a healthy stomach lining. While NSAIDs are partially effective in treating pain and inflammation, side effects such as stomach irritation and bleeding, kidney toxicity, and peptic ulcers make them less appealing for long-term use. A primary cause of NSAID toxicity is over-inhibition of the COX-1 enzyme.

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One Response to “Fighting Inflammation by Inhibiting LOX Enzymes with Boswella”

  1. Arrow Durfee Says:

    Another poster sent me this. I don’t know about this brand but I think Acai is worth looking into.

    After almost killing me with arthritis drugs, I finally have found one natural remedy that works. Acai juice is a natural inflammatory and highly anti oxidant. It does not bother the stomach and has no drugs. It relieves the inflammation and keeps the pain away. It works also on injury pain. If one takes 2 -4 oz. everyday the stiffness, pain and inflammation will go away and you will have energy and feel much better. For information contact