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The Nitty Grit of Making Thyroid Hormone (Thyroxine)

13th March 2007 by Arrow Durfee Posted in Uncategorized

Another consideration in hypo and hyper thyroid is supplementation with Hydrochloric Acid. (HCL)

Linkages, split by pepsin are those peptide bonds joining the amino group of phenylalanine, or tyrosine, being joined to another amino aid. Pepsin has a very well known mechanism of splitting the peptide bonds, which join phenylalanine or tyrosine to other amino acids.

One must not only consider the quantity of thyroid hormone in hypo or hyper conditions, but also the quality.

You want to make sure that the basic building blocks of the hormones are present, and surely, iodine is a leading one, but it is not the only one. The amino acid tyrosine is a basic building block. This amino is synthesized from phenylalanine. It is necessary to have sufficient HCL to convert pepsinogen into pepsinogen. Pepsin is required to split the bonds of phenylalaine so that tyrosine is split off.

Of course tyrosine is what all that iodine binds to to eventually form tetraiodthyroxine or simply thyroxine. HCL should be one of the first choices in supplementation for thyroid problems because it helps form the active enzyme pepsin from pepsinogen.

So, since we already know that many people, especially people 40 and over are deficient in HCL it is the logical starting place.
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